Table 1. Summary of selected studies on exercise therapy for shoulder dysfunction in patients with breast cancer

No. Author Country Sample size (study type) Intervention type Duration (study type) Key outcomes
1 Lauridsen et al.5 Denmark 62/77 (RCT) Early exercise & physical therapy 6 months Early exercise & physical therapy improved shoulder motion and function significantly.
2 McNeely et al.1 Canada Meta-analysis (SR) Exercise interventions (various types) Systematic review Consistent positive effects on shoulder function, pain reduction, and quality of life.
3 De Groef et al.3 Belgium Systematic review (SR) Resistance + mobility training vs. control Systematic review Improved ROM and strength; no increase in lymphedema risk.
4 McNeely et al.22 Canada Cochrane review (SR) Exercise interventions for upper-limb dysfunction Systematic review Strong evidence for exercise effectiveness in reducing pain and improving upper limb function
5 Courneya et al.23 Canada 121/121 (RCT) Aerobic + resistance training vs. usual care 6 months Enhanced physical function and upper body strength.
6 Battaglini et al.4 USA Systematic review (SR) Individualized exercise rehabilitation Systematic review Improved ROM, reduced pain, and cancer-related fatigue.
7 Sagen et al.24 Norway 104/100 (RCT) Stretching + ROM vs. usual care 6 months Improved physical activity and decreased shoulder pain in the exercise group.
8 Schmitz et al.8 USA 71/70 (RCT) Progressive weight training vs. no exercise 12 months No lymphedema increase; improved strength and arm function.
* IG/CG = intervention group/control group (for RCTs).
* RCT = randomized controlled trials; ROM = range-of-motion; SR = systematic review; meta-analysis = included quantitative synthesis.